The room above this has no doors.Using Mom's Pad against a Fat Fly may cause the fly to freeze and become invincible through the items duration, in which case can only receive damage by any other means except Isaac's tears. Secret rooms in XL dungeons can have regular rooms in them.
No sound effect for the Monstro's Tooth item.Getting killed can cause the music for a room/floor to reset.On the Character Selection Screen, if you use Arrow Keys on the Keyboard to switch between characters, no clicking sound will be played.The same thing happens with the first boss before Mom's Heart in an XL The Womb/ Utero. When fighting the first boss in an XL Depths/ Necropolis, the music for Mom's battle will play, regardless of the fact that the boss is Mom or not.If you leave a Challenge Room or a Boss Challenge Room (By teleporting out or dying with an extra life), the challenge music won't stop until the point where it would loop.